STUDYING OF THE ASSOCIATION BETWEEN HLA-G GENE POLYMORPHISM AND RISK RECURRENT MISCARRIAGE IN WOMEN WITH PERSISTENT BACTERIAL-VIRAL INFECTION
- 作者: Gordeeva L.A.1, Voronina E.N.2, Polenok E.G.1, Mun S.A.1, Olennikova R.V.3, Filipenko M.L.2, Glushkov A.N.1
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隶属关系:
- Federal Research Center of Coal and Coal Chemistry SB RAS (Institute of Human Ecology SB RAS)
- Institute of Chemical Biology and Fundamental Medicine SB RAS
- Kemerovo Regional Clinical Hospital, Genetic Consultation
- 期: 卷 22, 编号 2-1 (2019)
- 页面: 218-220
- 栏目: ORIGINAL ARTICLES
- URL: https://medbiosci.ru/1028-7221/article/view/119604
- DOI: https://doi.org/10.31857/S102872210006466-7
- ID: 119604
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全文:
详细
The associations between polymorphisms HLA-G (rs41551813, rs12722477, rs41557518 and rs16375) and recurrent miscarriage and risk of recurrent miscarriage (RM) in women with persistent bacterial-viral infection were investigated. It is found that the HLA-G rs12722477 110Ile allele is associated with the risk of RM only in women with persistent bacterial-viral infection (OR=2,49 (1,91–5,21); Pс=0,04).
作者简介
L. Gordeeva
Federal Research Center of Coal and Coal Chemistry SB RAS (Institute of Human Ecology SB RAS)
编辑信件的主要联系方式.
Email: ihe@kemtel.ru
PhD, leading researcher of Laboratory Immunogenetics,
Kemerovo
俄罗斯联邦E. Voronina
Institute of Chemical Biology and Fundamental Medicine SB RAS
PhD, researcher of Laboratory Pharmacogenomics,
Novosibirsk
俄罗斯联邦E. Polenok
Federal Research Center of Coal and Coal Chemistry SB RAS (Institute of Human Ecology SB RAS)
PhD, leading researcher of Laboratory Immunochemistry,
Kemerovo
俄罗斯联邦S. Mun
Federal Research Center of Coal and Coal Chemistry SB RAS (Institute of Human Ecology SB RAS)
PhD, senior researcher of Laboratory Immunogenetics,
Kemerovo
俄罗斯联邦R. Olennikova
Kemerovo Regional Clinical Hospital, Genetic Consultation
geneticist,
Kemerovo
俄罗斯联邦M. Filipenko
Institute of Chemical Biology and Fundamental Medicine SB RAS
PhD, Head of Laboratory Pharmacogenomics,
Novosibirsk
俄罗斯联邦A. Glushkov
Federal Research Center of Coal and Coal Chemistry SB RAS (Institute of Human Ecology SB RAS)
MD, deputy director,
Kemerovo
俄罗斯联邦参考
- L. Lynge Nilsson, S. Djurisic, T. V. Hviid. Controlling the Immunological Crosstalk during Conception and Pregnancy: HLA-G in Reproduction. Front Immunol. 2014, 13, 198, https://doi.org/10.3389/fimmu.2014.00198
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