NANO AND MICRODIMENSIONAL PARTICLES - A NEW LINK IN THE ETIOLOGY OF PERIIMPLANTITA

At present, it is being assumed that developments of inflammatory complications accompanying long-term functioning of dental implants in the patient's mouth, are correlated with the development of such diseases as mucositis and peri-implantitis. The pathogenesis of these dental implant complications remains, in our opinion, unexplored in terms of the role of immunological component in the mechanism of acute and chronic inflammation, which in turn requires research aimed at identifying the true causes, which may be proven biologically. It is being observed that, with standardized manufacturing techniques in use when it comes to the practical use of dental implants themselves, the clinical picture of their long-term use is personalized, which in turn can manifest in diminution of bone tissue and require surgical revision or reimplantation. The main causes of these inflammatory complications are correlated with personalized bacterial microenvironment, forming a biofilm on the surface of the dental implant in the patient's mouth, as well as with inadequate distribution of functional pressure connected with the manufacturing and use of the prosthesis. The role of emission of nano and microsized metal particles distributed in the oxide layer of the dental implants manufactured based on the TiO₂ alloy and their involvement in long-term interstitial interaction, has not been studied yet. This fact makes it necessary to conduct scientific studies on the immunological aspects of tissue repair at the cellular and molecular levels, and opens up a new perspective on the study of results when it comes to personification of dental implantation.

периимплантит, мукозит, нано и микроразмерные частицы, иммунологические аспекты, periimplantitis, mucositis, nano and microsized particles, immunological aspects