CHANGES IN PHAGOCYTOSIS PARAMETERS WITH A MARKER OF PHAGOSOME ACIDIFICATION pHrodo™ UNDER-ZYMOSAN-INDUCED PERITONITIS IN RATS
- 作者: Shilov S.J.1,2, Shilov J.I.1,2, Tulyaev Y.A.1, Barkov S.Y.2
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隶属关系:
- “Institute of Ecology and Genetics of Microorganisms of the Ural Branch of the Russian Academy of Sciences” – a branch of the PFRC UB RAS
- Acad. E. A. Wagner Perm State Medical University
- 期: 卷 22, 编号 2-2 (2019)
- 页面: 984-986
- 栏目: ORIGINAL ARTICLES
- URL: https://medbiosci.ru/1028-7221/article/view/120169
- DOI: https://doi.org/10.31857/S102872210006497-1
- ID: 120169
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全文:
详细
The changes in phagocytosis under 12-hour zymosan-induced peritonitis in rats were investigated using flow laser cytometry using zymosan labeled with pH-sensitive flurochrome green pHrodo™ (Thermo Fisher Scientifi c). An increase in the absolute parameters of phagocytosis was found in the study of peritoneal exudate cells, blood leukocytes and bone marrow cells in rats with peritonitis in comparison with intact animals.
作者简介
S. Shilov
“Institute of Ecology and Genetics of Microorganisms of the Ural Branch of the Russian Academy of Sciences” – a branch of the PFRC UB RAS;Acad. E. A. Wagner Perm State Medical University
编辑信件的主要联系方式.
Email: stshilov@mail.ru
PhD, MD, Junior Researcher,
Perm
俄罗斯联邦Ju. Shilov
“Institute of Ecology and Genetics of Microorganisms of the Ural Branch of the Russian Academy of Sciences” – a branch of the PFRC UB RAS;Acad. E. A. Wagner Perm State Medical University
PhD, MD, Associate Professor, Leading Researcher,
Perm
俄罗斯联邦Ya. Tulyaev
“Institute of Ecology and Genetics of Microorganisms of the Ural Branch of the Russian Academy of Sciences” – a branch of the PFRC UB RAS
Aspirant,
Perm
俄罗斯联邦S. Barkov
Acad. E. A. Wagner Perm State Medical University
Student,
Perm
俄罗斯联邦参考
- Zhang R., Kobayashi Y., Kazumura K., Tsuchiya H., Morishita N., Inagawa H., Soma G. Development of an evaluation device for phagocytic activity of new phagocytes using simple and pH-sensitive particles that do not require pre-treatment. Anticancer Res. 2016, 36(7), 3613–3618.
- Kapellos T. S., Taylor L., Lee H., Cowley S. A., James W. S.., Iqbal A. J., Greaves D. R. A novel real time imaging platform to quantify macrophage phagocytosis. Biochemical Pharmacology 2016, 116, 107–119.
- Шилов Ю. И., Шилов С. Ю., Жукова А. Е., Барков С. Ю., Петухова А. А. Изменение уровня ацидификации фагосом у крыс в зависимости от фазы эстрального цикла. Российский иммунологический журнал 2016, том 10 (19), № 2 (1), 183–184.
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