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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">Medicine and Biotechnology</journal-id><journal-title-group><journal-title xml:lang="en">Medicine and Biotechnology</journal-title><trans-title-group xml:lang="ru"><trans-title>Медицина и биотехнологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">3034-6231</issn><issn publication-format="electronic">3034-6258</issn><publisher><publisher-name xml:lang="en">National Research Mordovia State University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">282177</article-id><article-id pub-id-type="doi">10.15507/3034-6231.001.202502.102-118</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Биотехнологии</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Biotechnologies</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Production of Functional Dairy Products using Algae-based Additives</article-title><trans-title-group xml:lang="ru"><trans-title>Получение функциональных молочных продуктов с использованием добавок на основе водорослей</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6437-3621</contrib-id><contrib-id contrib-id-type="scopus">6603368347</contrib-id><contrib-id contrib-id-type="researcherid">D-2680-2015</contrib-id><contrib-id contrib-id-type="spin">3339-5067</contrib-id><name-alternatives><name xml:lang="en"><surname>Shutova</surname><given-names>Vitalina V.</given-names></name><name xml:lang="ru"><surname>Шутова</surname><given-names>Виталина Викторовна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Cand.Sci. (Biol.), Associate Professor, Associate Professor of the Department of Biotechnology and Biochemistry, Faculty of Biotechnology and Biology</p></bio><bio xml:lang="ru"><p>кандидат биологических наук, доцент, доцент кафедры биотехнологии и биохимии факультета биотехнологии и биологии </p></bio><email>vshutova@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6542-2667</contrib-id><contrib-id contrib-id-type="scopus">7003790280</contrib-id><contrib-id contrib-id-type="researcherid">E-4556-2014</contrib-id><contrib-id contrib-id-type="spin">8427-2359</contrib-id><name-alternatives><name xml:lang="en"><surname>Revin</surname><given-names>Viktor V.</given-names></name><name xml:lang="ru"><surname>Ревин</surname><given-names>Виктор Васильевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Dr.Sci. (Biol.), Professor, Dean of the Faculty of Biotechnology and Biology</p></bio><bio xml:lang="ru"><p>доктор биологических наук, профессор, декан факультета биотехнологии и биологии </p></bio><email>revinvv2010@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">National Research Mordovia State University</institution></aff><aff><institution xml:lang="ru">Национальный исследовательский Мордовский государственный университет</institution></aff></aff-alternatives><content-language>ru</content-language><pub-date date-type="pub" iso-8601-date="2025-06-23" publication-format="electronic"><day>23</day><month>06</month><year>2025</year></pub-date><pub-date date-type="collection"><year>2025</year></pub-date><volume>1</volume><issue>2</issue><issue-title xml:lang="ru"/><fpage>102</fpage><lpage>118</lpage><history><date date-type="received" iso-8601-date="2025-03-04"><day>04</day><month>03</month><year>2025</year></date><date date-type="accepted" iso-8601-date="2025-04-24"><day>24</day><month>04</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="ru">Copyright ©; 2025, Шутова В.В., Ревин В.В.</copyright-statement><copyright-statement xml:lang="en">Copyright ©; 2025, Shutova V.V., Revin V.V.</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Шутова В.В., Ревин В.В.</copyright-holder><copyright-holder xml:lang="en">Shutova V.V., Revin V.V.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://medbiosci.ru/MedBiotech/article/view/282177">https://medbiosci.ru/MedBiotech/article/view/282177</self-uri><abstract xml:lang="en"><p><italic><bold>Introduction. </bold></italic>Dairy products play an important role in human nutrition due to their dietary and medicinal properties, good digestibility and pleasant taste. Algae possess high nutritional value due to their abundant content of fibers, minerals, and polyunsaturated fatty acids. It is expedient to enhance the nutritional value and enrich dairy products with easily digestible micronutrients and vitamins, particularly iodine, which is deficient in our region. <italic>The aim of this study</italic> is to explore the prospects and challenges associated with producing functional dairy products using algae-based additives.<italic><bold>Materials and methods.</bold></italic> A thematic search for scientific works employingkeywords such as “functional dairy products,” “dairy products”, “algae,” “powder from Laminaria japonica,” and “Laminaria” was conducted within the cohort of full-text publications available on the research-oriented social network ResearchGate, as well as in the scientific electronic libraries eLibrary, PubMed, and Google Scholar during the period from 2001 to 2024. During selection, journal ratings and article citation counts were taken into account.<italic><bold>Results. </bold></italic>This work revealed that proteins, peptides, fats, oligosaccharides,vitamins, and minerals present in milk and dairy products can exert physiological effects on the body and be utilized as functional and nutraceutical ingredients to promote health and reduce disease risk. Furthermore, dairy products serve as an ideal matrix for incorporating non-dairy functional components owing to their excellent compatibility with other ingredients and superior taste and nutritional qualities. Brown algae have been identified as valuable sources of structurally diverse bioactive compounds, which are utilized in food, functional foods, and medicinal substances. It has been proven that dairy products are consumed byall age groups, making it highly reasonable to employ algae-based additives in their production. Algae from Laminaria japonica was incorporated into recipes for cottage cheese spread, cottage cheese cream, cheeses, yogurts, and other products. It was observed that higher doses of seaweeds resulted in changes in product flavor, color, and sometimes consistency, thereby impairing organoleptic properties. The most successful formulation proved to be cottage cheese with the addition of 2% algae powder . The use of the additive had minimal impact on the organoleptic characteristics of the fermented milk product, while its iodine content qualified it as a functional product since one serving contained the dailyiodine requirement for humans.<italic><bold>Discussion and conclusion. </bold></italic>Utilizing seaweeds as a component in functional dairy products will open new horizons for the food industry, offering both nutritional and therapeutic-prophylactic advantages. Developments in this field will enable the creation of novel functional products that meet consumer expectations. Enrichment of food and beverage products with seaweeds could be an effective means ofpopularization; however, success may depend on the type of product, as there may be limitations related to organoleptic characteristics (appearance, taste, texture, etc.).</p></abstract><trans-abstract xml:lang="ru"><p><italic><bold>Введение. </bold></italic>Молочные продукты играют важную роль в питании человека благодаря своим диетическим и лечебным свойствам, хорошей усвояемости и приятному вкусу. Морские водоросли обладают высокой питательной ценностью за счет большого содержания волокон, минералов и полиненасыщенных жирных кислот. Целесообразной представляется задача повышения пищевой ценности, а также обогащения молочных продуктов легкоусвояемыми микроэлементами и витаминами, в частности дефицитным для нашего региона йодом. <italic>Цель исследования</italic> – изучение перспектив и проблем получения функциональных молочных продуктов с использованием добавок на основе водорослей.<italic><bold>Материалы и методы.</bold></italic> Проведен тематический поиск научных работ по ключевым словам «функциональные молочные продукты», «молочные продукты», «водоросли», «порошок из ламинарии японской», «ламинария» в когорте полнотекстовых публикаций, представленных в научно-информационной социальной сети ResearchGate, а также в научных электронных библиотеках eLibrary, PubMed, Google Scholar в 2001–2024 гг. При отборе учитывали рейтинг журналов и количество цитирований статей.<italic><bold>Результаты исследования.</bold></italic> Выявлено, что содержащиеся в молоке и молочных продуктах белки, пептиды, жиры, олигосахариды, витамины и минералы способны оказывать физиологическое воздействие на организм и могут использоваться в качестве функциональных и нутрицевтических ингредиентов для укрепления здоровья и снижения риска заболеваний. Кроме того, молочные продукты являются идеальной матрицей для внесения немолочных функциональных компонентов благодаря их отличной совместимости с другими ингредиентами, превосходным вкусовым и питательным свойствам. Определено, что бурые морские водоросли являются ценными источниками структурно разнообразных биологически активныхсоединений, используемых в качестве пищевых, функциональных продуктов питания и лекарственных веществ. Доказано, что молочные продукты употребляются всеми возрастными категориями населения, поэтому применение добавок на основе водорослей при их производстве вполне целесообразно. Водорослевую добавку использовали в рецептурах творожной массы, творожного крема, сыров, йогуртов и других продуктов. Обнаружено, что высокие дозы водорослей приводят к изменению вкуса и цвета продукта, а иногда и консистенции, что ухудшает органолептические свойства. Наиболее удачным вариантом рецептуры оказалась творожная масса с добавлением порошка из ламинарии японской в количестве 2 %. Применение добавки не оказало сильного влияния на органолептические свойства кисломолочного продукта, а по содержанию йода его можно отнести к функциональным продуктам, поскольку в одной порции содержалась суточная норма йода для человека.<italic><bold>Обсуждение и заключение.</bold></italic> Использование водорослей в качестве компонента функциональных молочных продуктов откроет новые горизонты для пищевой промышленности, предлагая питательные и лечебно-профилактические преимущества. Разработки в этой области позволят получить новые функциональные продукты, которые будут соответствовать ожиданиям потребителей. Обогащение продуктов питания и напитков водорослями может быть хорошим способом их популяризации, однако это будет зависеть от вида продукта, поскольку могут существовать ограничения, связанные с органолептическими характеристиками (внешний вид, вкус, текстура и т. д.).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>водоросли</kwd><kwd>порошок из ламинарии японской</kwd><kwd>казеин</kwd><kwd>функциональные продукты питания</kwd><kwd>йодная недостаточность</kwd><kwd>кисломолочные продукты</kwd><kwd>пищевые добавки</kwd><kwd>плавленые сыры</kwd></kwd-group><kwd-group xml:lang="en"><kwd>algae</kwd><kwd>powder from Laminaria japonica</kwd><kwd>casein</kwd><kwd>functional foods</kwd><kwd>iodine deficiency</kwd><kwd>fermented dairy products</kwd><kwd>food additives</kwd><kwd>processed cheeses</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Chandrapala J., Zisu B. Novel Trends in Engineered Milk Products. The Journal of Dairy Research. 2016;83(3):268–280. https://doi.org/10.1017/S0022029916000479</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Bengoa A.A., Iraporda C., Acurcio L.B., de Cicco Sandes S.H, Costa K., Guimarães G.M. et al. Physicochemical, Immunomodulatory and Safety Aspects of Milks Fermented with Lactobacillus Paracasei Isolated from Kefir. Food Research International (Ottawa, Ont.). 2019;123:48–55. https://doi.org/10.1016/j.foodres.2019.04.041</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Wang Y., Xing M., Cao Q., Ji A., Liang H., Song Sh. Biological Activities of Fucoidan and the Factors Mediating Its Therapeutic Effects: A Review of Recent Studies. Marine Drugs. 2019;17(3):183. https://doi.org/10.3390/md17030183</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Gul O., Mortas M., Atalar I., Dervisoglu M., Kahyaoglu T. Manufacture and Characterization of Kefir Made from Cow and Buffalo Milk, Using Kefir Grain and Starter Culture. Journal of Dairy Science. 2015;98(3):1517–1525. https://doi.org/10.3168/jds.2014-8755</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Aryana K.J., Olson D.W. A 100-Year Review: Yogurt and Other Cultured Dairy Products. Journal of Dairy Science. 2017;100(12):9987–10013. https://doi.org/10.3168/jds.2017–12981</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Makwana M., Hati S. Fermented Beverages and Their Health Benefits. Fermented Beverages. 2019;5:1–29. https://doi.org/10.1016/B978-0-12-815271-3.00001-4</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Magan J.B., O′Callaghan T.F., Kelly A.L., McCarthy N.A. Compositional and Functional Properties of Milk and Dairy Products Derived from Cows Fed Pasture or Concentrate‐Based Diets. Comprehensive Reviews in Food Science and Food Safety. 2021;20(3):2769–2800. https://doi.org/10.1111/1541-4337.12751</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Hadjimbei E., Botsaris G., Chrysostomou S. Beneficial Effects of Yoghurts and Probiotic Fermented Milks and Their Functional Food Potential. Foods. 2022;11(17):2691. https://doi.org/10.3390/foods11172691</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Khalaf A.T., Wei Y., Alneamah S.J.A., Al-Shawi S.G., Kadir S.Y.A., Zainol J. et al. What is New in the Preventive and Therapeutic Role of Dairy Products as Nutraceuticals and Functional Foods? BioMed Research International. 2021;2021:8823222. https://doi.org/10.1155/2021/8823222</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Abdi-Moghadam Z., Darroudi M., Mahmoudzadeh M., Mohtashami M., Jamal A.M., Shamloo E. et al. Functional Yogurt, Enriched and Probiotic: A Focus on Human Health. Clinical Nutrition ESPEN. 2023;57:575–586. https://doi.org/10.1016/j.clnesp.2023.08.005</mixed-citation></ref><ref id="B11"><label>11.</label><citation-alternatives><mixed-citation xml:lang="en">Kanareikin V.I., Rebezov M.B., Bikbova R.A. [New Functional Milk-Plant Yogurt]. Aktual`ny`e problemy` intensivnogo razvitiya zhivotnovodstva = Actual Problems of Intensive Development of Animal Husbandry. 2016;19(2):255–260. (In Russ., abstract in Eng.). https://elibrary.ru/wctpxd</mixed-citation><mixed-citation xml:lang="ru">Канарейкин В.И., Ребезов М.Б., Бикбова Р.А. Новый функциональный молочно-растительный йогурт. Актуальные проблемы интенсивного развития животноводства. 2016:19(2):255–260. https://elibrary.ru/wctpxd</mixed-citation></citation-alternatives></ref><ref id="B12"><label>12.</label><mixed-citation>Gul O., Atalar I., Mortas M., Dervisoglu M. Rheological, Textural, Colour and Sensorial Properties of Kefir Produced with Buffalo Milk Using Kefir Grains and Starter Culture: a Comparison with Cows’ Milk Kefir. International Journal of Dairy Technology. 2018;71(5):73–80. https://doi.org/10.1111/1471-0307.12503</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Yılmaz İ., Dolar M.E., Özpınar H. Effect of Administering Kefir on the Changes in Fecal Microbiota and Symptoms of Inflammatory Bowel Disease: a Randomized Controlled Trial. The Turkish Journal of Gastroenterology. 2019;30(3):242–253. https://doi.org/10.5152/tjg.2018.18227</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>O’Brien K.V., Stewart L.K., Forney L.A., Aryana K.J., Prinyawiwatkul W., Boeneke C.A. The Effects of Postexercise Consumption of a Kefir Beverage on Performance and Recovery during Intensive Endurance Training. Journal of Dairy Science. 2015;98(11):7446–7449. https://doi.org/10.3168/jds.2015-9392</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Sharifi M., Moridnia A., Mortazavi D., Salehi M., Bagheri M., Sheikhi A. Kefir: a Powerful Probiotics with Anticancer Properties. Medical Oncology. 2017;34(11):183. https://doi.org/ 10.1007/s12032-017-1044-9</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Alihosseini N., Moahboob S.A., Farrin N., Mobasseri M., Taghizadeh A., Ostadrahimi A.R. Effect of Probiotic Fermented Milk (Kefir) on Serum Level of Insulin and Homocysteine in Type 2 Diabetes Patients. Acta Endocrinologica (Bucharest). 2017;13(4):431–436. https://doi.org/10.4183/aeb.2017.431</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Fathi Y., Ghodrati N., Zibaeenezhad M.-J., Faghih Sh. Kefir Drink Causes a Significant Yet Similar Improvement in Serum Lipid Profile, Compared with Low-Fat Milk, in a Dairy-Rich Diet in Overweight or Obese Premenopausal Women: a Randomized Controlled Trial. Journal of Clinical Lipidology. 2017;11(1):136–146. https://doi.org/10.1016/j.jacl.2016.10.016</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Tu M.-Y., Chen H.-L., Tung Y.-T., Kao Ch.-Ch., Hu F.-Ch., Chen Ch.-M. Short-Term Effects of Kefir-Fermented Milk Consumption on Bone Mineral Density and Bone Metabolism in a Randomized Clinical Trial of Osteoporotic Patients. Public Library of Science ONE. 2015;10(12):e0144231. https://doi.org/ 10.1371/journal.pone.0144231</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>Ton A.M.M., Campagnaro B.P., Alves G.A., Aires R., Zambom Côco L., Arpini C.M. et al. Oxidative Stress and Dementia in Alzheimer’s Patients: Effects of Synbiotic Supplementation. Oxidative Medicine and Cellular Longevity. 2020;14:2638703. https://doi.org/10.1155/2020/2638703.2638703</mixed-citation></ref><ref id="B20"><label>20.</label><mixed-citation>Mert H., Yılmaz H., Irak K., Yıldırım S., Mert N. Investigation of the Protective Effect of Kefir Against Isoproterenol Induced Myocardial Infarction in Rats. Korean Journal for Food Science of Animal Resources. 2018;38(2):259–272. https://doi.org/10.5851/kosfa.2018.38.2.259</mixed-citation></ref><ref id="B21"><label>21.</label><mixed-citation>Hsu Y.-J., Huang W.-C., Lin J.-S., Chen Y.-M., Ho Sh.-T., Huang Ch.-Ch. et al. Kefir Supplementation Modifies Gut Microbiota Composition, Reduces Physical Fatigue, and Improves Exercise Performance in Mice. Nutrients. 2018;10(7):862. https://doi.org/10.3390/nu10070862</mixed-citation></ref><ref id="B22"><label>22.</label><mixed-citation>Bengoa A.A., Llamas M.G., Iraporda C., Dueñas M.T., Abraham A.G., Garrote G.L. Impact of Growth Temperature on Exopolysaccharide Production and Probiotic Properties of Lactobacillus Paracasei Strains Isolated from Kefir Grains. Food Microbiology. 2018;69:212–218. https://doi.org/10.1016/j.fm.2017.08.012</mixed-citation></ref><ref id="B23"><label>23.</label><mixed-citation>Gamba R.R., Yamamoto S., Abdel-Hamid M., Sasaki T., Michihata T., Koyanagi T. et al. Chemical, Microbiological, and Functional Characterization of Kefir Produced from Cow’s Milk and Soy Milk. International Journal of Microbiology. 2020;(1):7019286. https://doi.org/10.1155/2020/7019286.7019286</mixed-citation></ref><ref id="B24"><label>24.</label><mixed-citation>Vieira C.P., Rosario A.I.L.S., Lelis C.A., Rekowsky B.S.S., Carvalho A.P.A., Rosário D.K.A. et al. Bioactive Compounds from Kefir and Their Potential Benefits on Health: A Systematic Review and Meta-Analysis. Oxidative Medicine and Cellular Longevity. 2021(1):9081738. https://doi.org/10.1155/2021/9081738</mixed-citation></ref><ref id="B25"><label>25.</label><citation-alternatives><mixed-citation xml:lang="en">Korshunova A.F., Fedotova N.A., Levchenko M.N. [Justification of the Technology of Functional Products Based on Cottage Cheese]. Eurasian Union of Scientists. 2015;11–3(20):69–72. (In Russ., abstract in Eng.). https://elibrary.ru/vkupxf</mixed-citation><mixed-citation xml:lang="ru">Коршунова А.Ф., Федотова Н.А., Левченко М.Н. Обоснование технологии функциональных изделий на основе творога. Евразийский союз ученых. 2015;11–3(20):69–72. https://elibrary.ru/vkupxf</mixed-citation></citation-alternatives></ref><ref id="B26"><label>26.</label><mixed-citation>Shiby V.K., Mishra H.N. Fermented Milks and Milk Products as Functional Foods – A Review. Critical Reviews in Food Science and Nutrition. 2013;53(5):482–496. https://doi.org/10.1080/10408398.2010.547398</mixed-citation></ref><ref id="B27"><label>27.</label><mixed-citation>Başçam Z., Ozcan T. Functional Properties of Fermented Milk Produced with Plant Proteins. LWT – Food Science and Technology. 2017;86:25–30. https://doi.org/10.1016/j.lwt.2017.07.025</mixed-citation></ref><ref id="B28"><label>28.</label><mixed-citation>Kumar H., Dhalari R., Guleria S., Sharma R., Cimler R., Dhanjal D.S. et al. Advances in the Concept of Functional Foods and Feeds: Applications of Cinnamon and Turmeric as Functional Enrichment Ingredients. Critical Reviews in Food Science and Nutrition. 2025;65(6):1144–1162. https://doi.org/10.1080/10408398.2023.2289645</mixed-citation></ref><ref id="B29"><label>29.</label><mixed-citation>Savatinova M., Ivanova M. Functional Dairy Products Enriched with Omega-3 Fatty Acids. Food Science and Applied Biotechnology. 2024;7(1):1–13. https://doi.org/10.30721/fsab2024.v7.i1.301</mixed-citation></ref><ref id="B30"><label>30.</label><mixed-citation>Boor K.J., Wiedmann M., Murphy S., Alcaine S. A 100-Year Review: Microbiology and Safety of Milk Handling. Journal of Dairy Science. 2017;100(12):9933–9951. https://doi.org/10.3168/jds.2017-12969</mixed-citation></ref><ref id="B31"><label>31.</label><mixed-citation>Colombo M., Castilho N.P., Todorov S.D., Nero L.A. Beneficial Properties of Lactic Acid Bacteria Naturally Present in Dairy Production. BMC Microbiology. 2018;18(1):219. https://doi.org/10.1186/s12866-018-1356-8</mixed-citation></ref><ref id="B32"><label>32.</label><mixed-citation>Das G., Paramithiotis S., Sivamaruthi B.S., Wijaya Ch.H., Suharta S., Sanlier N. et al. Traditional Fermented Foods with Anti-Aging Effect: A Concentric Review. Food Research International (Ottawa, Ont.). 2020;134:109269. https://doi.org/10.1016/j.foodres.2020.109269</mixed-citation></ref><ref id="B33"><label>33.</label><citation-alternatives><mixed-citation xml:lang="en">Klyuchnikova D.V., Kuznetsova A.A., Krikunov A.V. Components-Dressers as a Mechanism to Expand the Range of Quark Products. Bulletin of the South Ural State University. Series: Food and Biotechnology. 2017;5(4):5–11. (In Russ., abstract in Eng.). https://doi.org/ 10.14529/food170401</mixed-citation><mixed-citation xml:lang="ru">Ключникова Д.В., Кузнецова А.А., Крикунов А.В. Компоненты-обогатители как механизм расширения ассортимента творожных продуктов. Вестник Южно-Уральского государственного университета. Серия: Пищевые и биотехнологии. 2017;5(4):5–11. https://doi.org/10.14529/food170401</mixed-citation></citation-alternatives></ref><ref id="B34"><label>34.</label><mixed-citation>Guneser O., Isleten Hosoglu M., Aydeniz B., Yuceer Y. Engineering of Milk-Based Beverages: Current Status, Developments, and Consumer Trends. Milk-based Beverages. 2019:1–37. https://doi.org/10.1016/B978-0-12-815504-2.00001-3</mixed-citation></ref><ref id="B35"><label>35.</label><citation-alternatives><mixed-citation xml:lang="en">Podkorytova A.V., Roshchina A.N., Evseeva N.V., Usov A.I., Golovin G.Yu., Popov A.M. Brown Algae of the Orders Laminariales and Fucales of the Sakhalin-Kuril Region: Stocks, Extraction, Use. Trudy VNIRO. 2020;181:235–256. (In Russ., abstract in Eng.). https://doi.org/10.36038/2307-3497-2020-181-235-256</mixed-citation><mixed-citation xml:lang="ru">Подкорытова А.В., Рощина А.Н., Евсеева Н.В., Усов А.И., Головин Г.Ю., Попов А.М. Бурые водоросли порядков Laminariales и Fucales Сахалино-Курильского региона: запасы, добыча, использование. Труды ВНИРО. 2020;181:235–256. https://doi.org/10.36038/2307-3497-2020-181-235-256</mixed-citation></citation-alternatives></ref><ref id="B36"><label>36.</label><mixed-citation>Wan-Loy C., Siew-Moi P. Marine Algae as a Potential Source for Anti-Obesity Agents. Marine Drugs. 2016;14(12):222. https://doi.org/10.3390/md14120222</mixed-citation></ref><ref id="B37"><label>37.</label><mixed-citation>Ścieszka S., Klewicka E. Algae in Food: A General Review. Critical Reviews in Food Science and Nutrition. 2019;59(21):3538–3547. https://doi.org/10.1080/10408398.2018.1496319</mixed-citation></ref><ref id="B38"><label>38.</label><mixed-citation>Maeda H. Nutraceutical Effects of Fucoxanthin for Obesity and Diabetes Therapy: a Review. Journal of Oleo Science. 2015;64(2):125–132. https://doi.org/10.5650/jos.ess14226</mixed-citation></ref><ref id="B39"><label>39.</label><mixed-citation>Shirosaki M., Koyama T. Laminaria Japonica as a Food for the Prevention of Obesity and Diabetes. Advances in Food and Nutrition Research. 2011;64:199–212. https://doi.org/10.1016/B978-0-12-387669-0.00015-6</mixed-citation></ref><ref id="B40"><label>40.</label><mixed-citation>Redway M.L., Combet E. Seaweed as Food: Survey of the UK Market and Appraisal of Opportunities and Risks in the Context of Iodine Nutrition. British Food Journal. 2023;125(10):3601–3622. https://doi.org/10.1108/BFJ-01-2023-0024</mixed-citation></ref><ref id="B41"><label>41.</label><mixed-citation>Roleda M.Y., Skjermo J., Marfaing H., Jónsdóttir R., Rebours C., Gietl A. et al. Iodine Content in Bulk Biomass of Wild-Harvested and Cultivated Edible Seaweeds: Inherent Variations Determine Species-Specific Daily Allowable Consumption. Food Chemistry. 2018;254:333–339. https://doi.org/10.1016/j.foodchem.2018.02.024</mixed-citation></ref><ref id="B42"><label>42.</label><mixed-citation>Stévant P., Rebours C., Chapman A. Seaweed Aquaculture in Norway: Recent Industrial Developments and Future Perspectives. Aquaculture International. 2017;25(12):1373–1390. https://doi.org/10.1007/s10499-017-0120-7</mixed-citation></ref><ref id="B43"><label>43.</label><mixed-citation>Kim S.K., Bhatnagar I. Physical, Chemical, and Biological Properties of Wonder Kelp – Laminaria. Advances in Food and Nutrition Research. 2011;64:85–96. https://doi.org/10.1016/B978-0-12-387669-0.00007-7</mixed-citation></ref><ref id="B44"><label>44.</label><mixed-citation>Ahmadi A., Moghadamtousi Z.S., Abubakar S., Zandi K. Antiviral Potential of Algae Polysaccharides Isolated from Marine Sources: A Review. BioMed Research International. 2015;1:825203. https://doi.org/0.1155/2015/825203</mixed-citation></ref><ref id="B45"><label>45.</label><mixed-citation>Cofrades S., Serdaroğlu M., Jiménez-Colmenero F. Design of Healthier Foods and Beverages Containing Whole Algae. In: Functional Ingredients from Algae for Foods and Nutraceuticals. Cambridge : Woodhead Publishing Limited. 2013;9:609–633. https://doi.org/10.1533/9780857098689.4.609</mixed-citation></ref><ref id="B46"><label>46.</label><mixed-citation>Li Y. L., Zhu Y. Z., Zheng P. H., Qu Zh.Y. Potentially Harmful Maillard Reaction Products in Food and Herb Medicines. Journal of Food Quality. 2021;8:1–11. https://doi.org/10.1155/2021/1798936</mixed-citation></ref><ref id="B47"><label>47.</label><mixed-citation>De B.G., Medeiros S., Souza M.P., Pinheiro A.C., Bourbon A.I., Cerqueira M. et al. Physical Characterization of an Alginate / Lysozyme Nano-Laminate Coating and Its Evaluation on “Coalho” Cheese Shelf Life. Food and Bioprocess Technology. 2014;7(4):1088–1098. https://doi.org/10.1007/s11947-013-1097-5</mixed-citation></ref><ref id="B48"><label>48.</label><mixed-citation>Sharma Khanal B.K., Bhandari B., Prakash S., Liu D., Zhou P., Bansal N. Modifying Textural and Microstructural Properties of Low Fat Cheddar Cheese Using Sodium Alginate. Food Hydrocolloids. 2018;83:97–108. https://doi.org/10.1016/j.foodhyd.2018.03.015</mixed-citation></ref><ref id="B49"><label>49.</label><mixed-citation>Anderson J.J., Sjöberg H.E. Dietary Calcium and Bone Health in the Elderly: Uncertainties about Recommendations. Nutrition Research. 2001;21(1):263–268. https://doi.org/10.1016/S0271-5317(00)00291-8</mixed-citation></ref><ref id="B50"><label>50.</label><citation-alternatives><mixed-citation xml:lang="en">Koval P.V., Shulgin Yu.P., Lazhentseva L.Yu., Zagorodnaya G.I. Probiotic Drinks Containing Iodine. Dairy Industry. 2005;(6):38–39. (In Russ). https://elibrary.ru/pveqsp</mixed-citation><mixed-citation xml:lang="ru">Коваль П.В., Шульгин Ю.П., Лаженцева Л.Ю., Загородная Г.И. Пробиотические йодсодержащие напитки. Молочная промышленность. 2005;(6):38–39. https://elibrary.ru/pveqsp</mixed-citation></citation-alternatives></ref><ref id="B51"><label>51.</label><mixed-citation>Jeon J.K. Effect of Chlorella Addition on the Quality of Processed Cheese. Journal of the Korean Society of Food Science and Nutrition. 2006;35(3):373–377. https://doi.org/10.3746/jkfn.2006.35.3.373</mixed-citation></ref><ref id="B52"><label>52.</label><mixed-citation>Iji P.A., Kadam M.M. Prebiotic Properties of Algae and Algae-Supplemented Products. In: Functional Ingredients from Algae for Foods and Nutraceuticals. Cambridge : Woodhead Publishing Limited. 2013;658–670. https://doi.org/10.1533/9780857098689.4.658</mixed-citation></ref><ref id="B53"><label>53.</label><mixed-citation>Rosa D.D., Dias M.M., Grześkowiak Ł.M., Reis S.A., Conceição L.L., Peluzio M.C.G. Milk Kefir: Nutritional, Microbiological and Health Benefits. Nutrition Research Reviews. 2017;30(1):82–96. https://doi.org/10.1017/S0954422416000275</mixed-citation></ref></ref-list></back></article>
