Neoadjuvant chemotherapy with Epirubicin / Cyclophosphamid high dose in locally advanced breast cancer (T2-T4/NO-N2/MO)

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Objective: The timing of chemotherapy (CHT) in relation to surgery has recently been the subject of intensive investigations. The response of the primary tumor is a reliable prognostic factor and can in addition be regarded as an “in vivo” chemosensitivity test Is it possible to achieve a higher rate of breast conserving therapy (UCT) on locally advanced breast cancer by neoadjuvant treatment? The efficiency on the primary tumor and on the lymphatic nodes will be presented.

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