The features of bone exchange at women of eproductive age after bilateral ovariectomy

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The research of bone exchange in 80 women after bilateral ovariectomy and in 120 patients in natural menopause with duration of estrogen deficiency 4,3±0,6 years and 4,2±0,8 years respectively was performed. There were used the modern techniques of BMD estimation (DEXA) and biochemical markers of bone remodeling - N-MID osteocalcin, Pyrilincs D, Beta-Cross Laps, alkaline phosphatase. The identical orientation of infringements of bone exchange in both groups was revealed. However, at women after ovariectomy the osteoresorption occured more actively, despite on younger age of participants of research that finds reflection in low values of BMD in all parts of skeleton and high occurrence of bone rarefication. The most informative markers of bone exchange, promoting early diagnostics of metabolic osteopathy were revealed.

作者简介

I. Zazerskaja

Academician I.P. Pavlov First St. Petersburg State Medical University

编辑信件的主要联系方式.
Email: info@eco-vector.com
俄罗斯联邦, 6-8 L'va Tolstogo Str., Saint Petersburg, 197022

L. Kuznetsova

Academician I.P. Pavlov First St. Petersburg State Medical University

Email: info@eco-vector.com
俄罗斯联邦, 6-8 L'va Tolstogo Str., Saint Petersburg, 197022

V. Jakovlev

Academician I.P. Pavlov First St. Petersburg State Medical University

Email: info@eco-vector.com
俄罗斯联邦, 6-8 L'va Tolstogo Str., Saint Petersburg, 197022

L. Alexandrova

Academician I.P. Pavlov First St. Petersburg State Medical University

Email: info@eco-vector.com
俄罗斯联邦, 6-8 L'va Tolstogo Str., Saint Petersburg, 197022

А. Djachuk

Central Medical and Sanitary Unit No. 1222

Email: info@eco-vector.com
俄罗斯联邦, Saint Petersburg

D. Niauri

Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott

Email: info@eco-vector.com
俄罗斯联邦, 3 Mendeleevskaya Line, Saint Petersburg, 199034

S. Selkov

Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott

Email: info@eco-vector.com
俄罗斯联邦, 3 Mendeleevskaya Line, Saint Petersburg, 199034

L. Dzhumaeva

FGU TsNIRRI Roszdrav

Email: info@eco-vector.com
俄罗斯联邦, Saint Petersburg

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2. Fig. 1. Prevalence of osteopenia and osteoporosis in the observation groups.

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3. Fig. 2. The content of biochemical markers of bone tissue metabolism in postmenopausal women (group II) and with SPEE (group I).

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4. Fig. 3. Distribution of BMD in subregions of the skeleton in women with STES (I) and postmenopausal women (II).

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