Pharmacological another problems of medical genetic consulting during pregnanc

The review of original and literature data dealing with case-reports of women, who used pharmacological reagents during pregnancies. Critical analysis of these data prooves the becessity of strictly individual approach for each woman. Personal recommendation of genetical councellor should be consider the biochemical mechanisms of the drug action,date of pregnancy doses an d duration of consumpyion. The inefficiency and general useless of invasive prenatal karyotyping of the fetus subjected to teratogenic agents are stressed. While repeated (dynamic) ultrasound examinations remains as a single feasible mean to estimate adverse effect of the drug during pregnanacy. Commercially available computerasid programms of teratogenic agents do not exclude routine medical- genetic councelling with subcequent invasive prenatal diagnosis because of the reasons not concerned with drug consumption.