电邮这篇文章 Role of atrial natriuretic peptide (ANP) in feto-placental and maternal circulation
- 作者: Polyanin A.A.1,2,3, Kogan I.J.1,2,3
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隶属关系:
- Research Institute of Obstetrics and Gynecology named after D.O. Ott, Russian Academy of Medical Sciences
- St. Petersburg State Medical University. acad. I. P. Pavlova
- Saint Petersburg State University
- 期: 卷 51, 编号 1 (2002)
- 页面: 25-32
- 栏目: Original study articles
- URL: https://medbiosci.ru/jowd/article/view/89948
- DOI: https://doi.org/10.17816/JOWD89948
- ID: 89948
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ANPwas measured in maternal cubital vein (M), umbilical vein (UV) and artery (UA) in 39 women at term delivery (23 vaginal, 16 caesarean): 15 - normal pregnancy; 24 pregnancies were complicated by placental insufficiency, 14 - by preeclampsia, 10 - by diabetes mellitus. Blood gases and pH in UA, UV were measured.
M, UA, UV ANPat caesarean section was similar to that in vaginal delivery (p>0,05). In normal and complicated pregnancies, UA ANPwas significantly higher than ANPin M and UV. In pregnancies complicated by diabetes mellitus, UV ANPwas higher than ANPin UA (21, 93 fmol/l and 13, 03 fmol/l). In pregnancies complicated by acute placental insufficiency, UV ANPwas significantly lower than that in UA in normal pregnancy (p<0,001). There is positive correlation between ANPconcentration and pH in UV.
Fetus is capable of ANPproduction. ANPmay be synthesized in the placenta.
Fetal hypoxia appears to be a potent stimulus for elevating of ANPplasma concentration.
作者简介
A. Polyanin
Research Institute of Obstetrics and Gynecology named after D.O. Ott, Russian Academy of Medical Sciences; St. Petersburg State Medical University. acad. I. P. Pavlova; Saint Petersburg State University
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Email: info@eco-vector.com
medical faculty
俄罗斯联邦, Saint Petersburg; Saint Petersburg; Saint peterburgI. Kogan
Research Institute of Obstetrics and Gynecology named after D.O. Ott, Russian Academy of Medical Sciences; St. Petersburg State Medical University. acad. I. P. Pavlova; Saint Petersburg State University
Email: info@eco-vector.com
medical faculty
俄罗斯联邦, Saint Petersburg; Saint Petersburg; Saint peterburg参考
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