Clinical and epidemiological features of cutaneous mastocytosis among the pediatric population of Moscow

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BACKGROUND: Cutaneous mastocytosis is a rare disease that primarily develops in childhood.

AIM: This study aimed to determine the clinical and epidemiological characteristics and frequency of detection of cutaneous mastocytosis among children in Moscow.

MATERIALS AND METHODS: A single-center epidemiological retrospective study was conducted. Data from Form № 12 of the federal statistical observation "Information on the number of diseases registered in patients living in the service area of a medical organization" were used as a statistical source of information. To calculate the incidence rate in intensive indicators per 100 thousand population, data on the population of Moscow for the period 2019–2022 were used.

RESULTS: Over the period 2019–2022, a gradual trend towards an increase in the number of newly identified cases of cutaneous mastocytosis in children and adolescents in Moscow was revealed. Number of initial applications from children and adolescents (0–17 years old) for this period increased by 4.8 times. The share of cutaneous mastocytosis in the structure of skin diseases and congenital anomalies (malformations) of the skin increases every year. In 2019, for every 1,834 pediatric visits (age category 0–17 years) regarding skin diseases, there was 1 case of mastocytosis; in 2020 the ratio was 1,863:1; in 2021 ― 491:1; in 2022 ― 376:1. Since 2019, there has been an increase in the primary incidence of cutaneous mastocytosis from 3.63 cases per 100,000 child population to 16.61 cases per 100,000 child population in 2022.

CONCLUSION: The increase in incidence in the pediatric population and the share of cutaneous mastocytosis in the structure of skin diseases in recent years demonstrates the need to generate interest and attention of the medical community to this pathology.

作者简介

Elena Kasikhina

Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology; Peoples' Friendship University of Russia

编辑信件的主要联系方式.
Email: kasprof@bk.ru
ORCID iD: 0000-0002-0767-8821

MD, Cand. Sci. (Med.)

俄罗斯联邦, Moscow; Moscow

Nikolay Potekaev

Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology; The Russian National Research Medical University named after N.I. Pirogov

Email: klinderma@mail.ru
ORCID iD: 0000-0002-9578-5490

MD, Dr. Sci. (Med.), Professor

俄罗斯联邦, Moscow; Moscow

Maisa Ivanova

Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology

Email: maisa961@mail.ru
ORCID iD: 0000-0002-7714-7970

MD, Dr. Sci. (Med.), Professor

俄罗斯联邦, Moscow

Olga Zhukova

Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology; Peoples' Friendship University of Russia

Email: klinderma@inbox.ru
ORCID iD: 0000-0001-5723-6573

MD, Dr. Sci. (Med.), Professor

俄罗斯联邦, Moscow; Moscow

Olga Novozhilova

Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology

Email: novozhilova.o@mail.ru
ORCID iD: 0000-0003-2897-3798
俄罗斯联邦, Moscow

Maria Ostretsova

Peoples' Friendship University of Russia

Email: ostretsova-mn@rudn.ru
ORCID iD: 0000-0003-3386-1467

MD, Cand. Sci. (Med.)

俄罗斯联邦, Moscow

Aizhan Okenaeva

Peoples' Friendship University of Russia

Email: okenaeva61@mail.ru
ORCID iD: 0000-0002-8094-0128
俄罗斯联邦, Moscow

参考

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