Email this article Psychoemotional and humoral changes in patients with combined reflux disorders
- Authors: Akhmedov V.A.1, Ostapenko VA1, Akhmedov VA1, Ostapenko VA1
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Affiliations:
- Омская медицинская академия
- Issue: Vol 81, No 2 (2009)
- Pages: 24-26
- Section: Editorial article
- URL: https://medbiosci.ru/0040-3660/article/view/30269
- ID: 30269
Cite item
Abstract
Aim. To investigate disorders of psychoemotional functions, humoral regulation (substance P) and duodenal motility (DM) in patients with combined refluxes for their differential correction.
Material and methods. A total of 60 patients with gastroesophageal and duodenogastric refluxes were examined.
Results. Patients with reflux disorders had more frequent and severe neurotic reactions. Humoral changes are associated with characteristics of psychoemotional regulation. The risk of subnormal levels of the substance P rises substantially in changes in the scales of anxiety, neurotic depression, hysterical reaction and autonomic disorders. Segmental duodenal motility regresses with lowering of plasmic levels of substance P.
Conclusion. Patients with combined reflux disorders have psychoemotional disorders, abnormal humoral regulation and duodenal motility necessitating a differential approach to treatment of such patients.
Material and methods. A total of 60 patients with gastroesophageal and duodenogastric refluxes were examined.
Results. Patients with reflux disorders had more frequent and severe neurotic reactions. Humoral changes are associated with characteristics of psychoemotional regulation. The risk of subnormal levels of the substance P rises substantially in changes in the scales of anxiety, neurotic depression, hysterical reaction and autonomic disorders. Segmental duodenal motility regresses with lowering of plasmic levels of substance P.
Conclusion. Patients with combined reflux disorders have psychoemotional disorders, abnormal humoral regulation and duodenal motility necessitating a differential approach to treatment of such patients.
Keywords
About the authors
Vadim Adil'evich Akhmedov
Омская медицинская академия
Email: v_akhmedov@mail.ru
научный сотрудник кафедры факультетской терапии; Омская медицинская академия
V A Ostapenko
V A Akhmedov
V A Ostapenko
References
- Lundell L., Myers J. C., Jamieson G. G. Is motility impaired in the entire upper gastrointestinal tract in patients with gastro-oesophageal reflux disease? Scand. J. Gastroenterol. 1996; 31: 131-135.
- Жуков Н. А., Ахмедов В. А., Турилова Н. С. Патология двенадцатиперстной кишки и ее роль в формировании рефлюксной болезни. Рос. гастроэнтерол. журн. 2001; 1: 73-80.
- Cox M. R., Radbury R. T., Harvey J. R. et al. Substance P stimulates sphincter of Oddi motilitu and inhibits trans-sphincteric flow in the Australian brush-tailed possum. Neurogastroenterol. Motil. 1998; 10: 165-173.
- Ахмедов В. А. Рефлюксная болезнь и органы-мишени. М.; 2007.
- Менделевич В. Д. Клиническая и медицинская психология. М.; 1999.
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