MORPHOLOGICAL CHANGES IN ENDOMETRY IN INFERTILE WOMEN UNDER CHRONIC INFLAMMATION

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Abstract

In the development of infertility, the role of chronic inflammatory diseases that are involved in the formation of the morphological basis for fertility decline is being actively considered. In the present study, a retrospective analysis of the results of the histological examination of the pipeline biopsy specimens of 64 women with an established diagnosis of chronic endometritis was carried out. The presence of cell inf ltration was shown in 67% of cases, as well as a combination of dystrophic and proliferative processes (33%), which in general may indicate the presence of persistent infection.

About the authors

A. P. Godovalov

Acad. E. A. Wagner Perm State Medical University

Author for correspondence.
Email: AGodovalov@gmail.com

Ph.D., l. r., Central Scientific Research Laboratory, Associate Professor of the Department of Microbiology and Virology,

Perm

Russian Federation

S. A. Toropitsyn

Acad. E. A. Wagner Perm State Medical University

student,

Perm

Russian Federation

T. I. Karpunina

Acad. E. A. Wagner Perm State Medical University

D. Sci.Biol. Professor of the Department of Microbiology and Virology,

Perm

Russian Federation

References

  1. Petrina M. A. B., Cosentino L. A., Wiesenfeld H. C., Darville T., Hillier S. L. Susceptibility of endometrial isolates recovered from women with clinical pelvic inflammatory disease or histological endometritis to antimicrobial agents. Anaerobe. 2019, 56, 61–65.
  2. Kimura F., Takebayashi A., Ishida M., Nakamura A., Kitazawa J., Morimune A., Hirata K., Takahashi A., Tsuji S., Takashima A., Amano T., Tsuji S., Ono T., Kaku S., Kasahara K., Moritani S., Kushima R., Murakami T. Review: Chronic endometritis and its effect on reproduction. J Obstet Gynaecol Res. 2019, doi: 10.1111/jog.13937. [Epub ahead of print].
  3. Годовалов А. П., Карпунина Т. И. Оценка эндогенной интоксикации у субфертильных женщин с хроническим эндометритом. Вестник современной клинической медицины. 2018, 11; 4, 25–28.

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Copyright (c) 2019 Godovalov A.P., Toropitsyn S.A., Karpunina T.I.

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