THE ROLE OF THE MONOCYTIC AND MACROPHAGAL SYSTEM IN THE DYNAMICS OF THE REPLACEMENT REGENERATION IN CASE OF THE ELASTIN BIOMATERIAL TRANSPLANTATION
- 作者: Nigmatullin R.T.1, Gizatullina E.R.1, Motygullin B.R.1
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隶属关系:
- The Russian Eye and Plastic Surgery Centre of the Russian Federation Health Ministry
- 期: 卷 20, 编号 2 (2017)
- 页面: 179-182
- 栏目: Articles
- URL: https://medbiosci.ru/1028-7221/article/view/119629
- ID: 119629
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详细
The article contains the results of the morphological investigations when subcutaneously transplanting two types of the elastin biomaterial: structurized and dispersed one (patent № 2440148). The experiments have been carried out on Wistar rats (n=59). The transplanted biomaterials were subjected to the stage-by-stage resorption with further formation of the connective tissue regenerate. When doing it, the cells of the macrophagal and fibroblastic differentiation come out as a unified morphofunctional system in which giant multinuclear cells are an indispensable element. Depending on the biomaterial structure there are singled out two histotopographic types of the replacement regeneration: frontal type for the structurized biomaterial and diffuse-locunar one for the dispersed biomaterial.
作者简介
R. Nigmatullin
The Russian Eye and Plastic Surgery Centre of the Russian Federation Health Ministry
编辑信件的主要联系方式.
俄罗斯联邦
E. Gizatullina
The Russian Eye and Plastic Surgery Centre of the Russian Federation Health Ministry俄罗斯联邦
B. Motygullin
The Russian Eye and Plastic Surgery Centre of the Russian Federation Health Ministry俄罗斯联邦
参考
- Anabami N., Mithieux S. M., Camci-Unal G., Dokmeci M. R., Weiss A. S., Khademhosseini A. Elastomeric recombinant protein-based biomateri-als. Biochemical Engineering Journal, 77(2013), 110-118.
- Derricks K. E., Rich C. B., Buczek-Thomas J.A., Nugent M. A. Ascorbate enhances elastin synthesis in 3D tissue-engineered pulmonary fibroblasts constructs. Tissue and Cell 2013, 45, 253-260.
- Нигматуллин Р. Т., Кутушев Р. З. Применение эластинового биоматериала в восстановительной хирургии стенок глазницы. «Практическая медицина» 2016, 6(98), 119-121.
- Мулдашев Э. Р., Нигматуллин Р. Т., Галимова В. У. и др. Пат. РФ № 2440148 // Бюл. изобр. 2012.№ 2
- Бабаева А. Г. Регенерация: факты и перспективы. Издательство РАМН, Москва, 2009, 336.
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