Email this article THE EFFECTIVENESS OF COMBINED TREATMENT OF DISSEMINATED MALIGNANT PLEURAL MESOTHELIOMA, A DESCRIPTION OF THE CLINICAL CASE
- Authors: Karpenko T.D.1, Bychkov M.B1
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Affiliations:
- N.N. Blokhin National Medical Research Center of Oncology
- Issue: Vol 22, No 5 (2017)
- Pages: 274-276
- Section: Articles
- URL: https://medbiosci.ru/1028-9984/article/view/40390
- DOI: https://doi.org/10.18821/1028-9984-2017-22-5-274-276
- ID: 40390
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Abstract
Modern approach to the individualization of the management of patients based on the careful observation for the minimal manifestations of the disease, prescription of pemetrexed at the first line of therapy, combination with platinum preparations and antiangiogenic targeted preparation bevazisumab allows control the disease at the advanced stage of pleural mezoteliom and support the good active state of patients during the long time.
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##article.viewOnOriginalSite##About the authors
Tat’yana D. Karpenko
N.N. Blokhin National Medical Research Center of Oncology
Email: katan4ik@list.ru
MD, Postgraduate of the Department of Chemotherapy of the Research Institute of Clinical Oncology, Moscow, 115478, Russian Federation Moscow, 115478, Russian Federation
M. B Bychkov
N.N. Blokhin National Medical Research Center of OncologyMoscow, 115478, Russian Federation
References
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- Яблонский П.К., Петров А.С. Злокачественная мезотелиома плевры. Практическая онкология. 2006; 3: 179-86.
- Vogelzang N.J., Rusthoven J.J., Symanowski J., Denham C., Kaukel E., Ruffie P. et al. Phase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma. J. Clin. Oncol. 2003; 21(14): 2636-44.
- Ceresoli G.L., Zucali P.A., Favaretto A.G. et al. Phase II study of pemetrexed plus carboplatin in malignant pleural mesothelioma. J. Clin. Oncol. 2006; 24: 1443-38.
- Zalcman G., Mazieres J., Margery J. et al. Bevacizumab for newly diagnosed pleural mesothelioma in the Mesothelioma Avastin Cisplatin Pemetrexed Study (MAPS): a randomised, controlled, open-label, phase 3 trial. Lancet. 2016; 387: 1405-14.
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