Email this article Clinical cases of treatment of hepatocellular carcinoma
- Authors: Lazarev SA1,2, Mamontov KG1,2, Manihas GM3, Antimonik NY.3
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Affiliations:
- КГБУЗ Алтайский краевой онкологический диспансер
- Алтайский филиал ФГБУ РОНЦ им. Н.Н.Блохина РАМН
- СПб ГБУЗ Городской клинический онкологический диспансер
- Issue: Vol 16, No 1 (2014)
- Pages: 65-69
- Section: Articles
- URL: https://medbiosci.ru/1815-1434/article/view/26953
- ID: 26953
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Abstract
The article presents the clinical cases of sorafenib treatment of hepatocellular carcinoma. The experience of the Russian oncologistsdoes not only confirm the results of the international clinical research, but also demonstrates the possibility of prolonged administration of the drug for more than 3-4 years against a backdrop of high efficiency and controlled security profile.
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##article.viewOnOriginalSite##About the authors
S A Lazarev
КГБУЗ Алтайский краевой онкологический диспансер; Алтайский филиал ФГБУ РОНЦ им. Н.Н.Блохина РАМН
K G Mamontov
КГБУЗ Алтайский краевой онкологический диспансер; Алтайский филиал ФГБУ РОНЦ им. Н.Н.Блохина РАМН
G M Manihas
СПб ГБУЗ Городской клинический онкологический диспансер
N Yu Antimonik
СПб ГБУЗ Городской клинический онкологический диспансер
References
- Практические рекомендации по лекарственному лечению больных первичным раком печени общества онкологов - химиотерапевтов (RUSSCO). Версия 2013; с. 229-36.
- EASL-EORTC Clinical Practice Guidelines: Management of hepatocellular carcinoma. J Hepatol 2012; 56: 908-43.
- Bruix J, Raoul J.L, Sherman M et al. Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma: subanalyses of a phase III trial. J Hepatol 2012; 57 (4): 821-9;
- Llovet J.M, Ricci S, Mazzaferro V et al. Sorafenib in advanced hepatocellular carcinoma. N Engl J Med 2008; 359 (4): 378-90.
- Marrero J et al. Final analysis of GIDEON (Global Investigation of therapeutic DEcisions in hepatocellular carcinoma and Of its treatment with sorafeNib) in >3000 sorafenib - treated patients: clinical findings in patients with liver dysfunction. Poster presented at the Annual Meeting of the American Society of Clinical Oncology, May 31 - June 4, 2013; Chicago, Illinois USA.
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