Rational contraception: minimizing the risks


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Abstract

The use of COCs, even low - and microdosed should be based on an individual assessment of the risk of thrombotic complications. It is advisable to combine the COC together with multivitamin complexes that affect the hemostatic system in the first place, vascular endothelial component (Duovit® for women). The therapeutic use of COCs in women high risk of VTE may together with antithrombotic drugs (heparin and LMWH).

About the authors

P A Kiryushchenkov

Research Center for Obstetrics, Gynecology and Perinatology of the Ministry of Health of the Russian Federation

Email: masha-kirmail@mail.ru
д-р мед. наук, рук. группы клинической гемостазиологии ФГБУ НЦАГиП им. акад. В.И.Кулакова 117997, Russian Federation, Moscow, ul. Akademika Oparina, d. 4

M A Tambovtseva

Research Center for Obstetrics, Gynecology and Perinatology of the Ministry of Health of the Russian Federation

мл. науч. сотр. группы клинической гемостазиологии ФГБУ НЦАГиП им. акад. В.И.Кулакова 117997, Russian Federation, Moscow, ul. Akademika Oparina, d. 4

References

  1. Kubba A, Guillebaud J, Anderson R.A, Mac Gregor E.A. Contraception. Lancet 2000; 356 (9245): 1913-9.
  2. Petitti D.B. Clinical practice. Combination estrogen - progestin oral contraceptives. N Engl J Med 2003; 349 (15): 1443-50.
  3. Руководство по контрацепции. Под ред. В.Н.Прилепской. М.: МЕДпресс - информ, 2006.
  4. Carpenter S.E.K, Rock J.A. Paediatric and Adolescent Gynecology. Philadelphia: Lippincott WW, 2000.
  5. Lidegaard O, Nielsen L.H, Skovlund C.W, Lokkegaard E. Venous thrombosis in users of non - oral hormonal contraception: follow - upstudy, Denmark 2001-2010. BMJ 2012; 344: 2990-8.
  6. Reid R, Leyland N, Wolfman W et al. SOGC clinical practice guidelines: Oral contraceptives and the risk of venous thromboembolism: an up - date: no. 252, December 2010. Int J Gynaecol Obstet 2011; 112 (3): 252-6.
  7. Момот А.П., Тараненко И.А., Цывкина Л.П. Эволюция представлений о тромбофилии и ее роли в проблемах репродукции человека. Акуш. и гинекол. 2013; 2: 4-9.
  8. James A.H, Tapson V.F, Goldhaber S.Z. Thrombosis during pregnancy and the postpartum period. Am J Obstet Gynecol 2005; 193 (1): 216-9.
  9. Folkeringa N, Brouwer J.L.P, Korteweg F et al. High risk of pregnancy - related venous thromboembolism in women with multiple thrombophilic defects. Br J Haematol 2007; 138 (1): 110-6.
  10. Ray J.G, Chan W.S. Deep vein thrombosis during pregnancy and the puerperium: a meta - analysis of the period of risk and the leg of presentation. Obstet Gynecol Surv 1999; 54 (4): 265-71.
  11. Sanson B.J, Simioni P, Tormene D et al. The incidence of venous thromboembolism in asymptomatic carriers of a deficiency of antithrombin, protein C, or protein S: a prospective cohort study. Blood 1999; 94 (11): 3702-6.
  12. Зайнулина М.С., Корнюшина Е.А., Бикмуллина Д.Р. Тромбофилия: этиологический фактор или патогенетический аспект осложненного течения беременности? Журн. акушерства и женских болезней. 2010; LIX (1): 18-30.
  13. Sammaritano L.R. Contraception in patients with systemic lupus erythematosus and antiphospholipid syndrome. Lupus 2014; 23 (12): 1242-5.
  14. Hugon-Rodin J, Gompel A, Plu-Bureau G. Epidemiology of hormonal contraceptives - related venous thromboembolism. Eur J Endocrinol 2014; 171 (6): R221-30.
  15. Tchaikovski S.N, Rosing J. Mechanisms of estrogen - induced venous thromboembolism. Thromb Res 2010; 126 (1): 5-11.
  16. Perrot-Applanat M, Cohen-Solal K, Milgrom E, Finet M. Progesterone receptor expression in human saphenous veins. Circulation 1995; 92 (10): 2975-83.
  17. Veljković M, Popovć J. Venous thromboembolism and oral contraception. Med Pregl 2010; 63 (5-6): 376-9.
  18. Sidney S, Petitti D.B, Soff G.A et al. Venous thromboembolic disease in users of low - estrogen combined estrogen - progestin oral contraceptives. Contraception 2004; 70: 3-10.
  19. Stegeman B.H, de Bastos M, Rosendaal F.R et al. Different combined oral contraceptives and the risk of venous thrombosis: systematic review and network meta - analysis. BMJ 2013; 347: f5298.
  20. De Bastos M, Stegeman B.H, Rosendaal F.R et al. Combined oral contraceptives: venous thrombosis. Cochrane Database of Systematic Reviews 2014; 3: CD010813.
  21. Plu-Bureau G, Maitrot-Mantelet L, Hugon-Rodin J, Canonico M. Hormonal contraceptives and venous thromboembolism: an epidemiological update. Best Practice & Research. Clin Endocrinol Metab 2013; 27 (1): 25-34.
  22. Martinez F, Ramirez I, Perez-Campos E et al. Venous and pulmonary thromboembolism and combined hormonal contraceptives. Systematic review and meta - analysis. Eur J Contracept Reprod Health Care 2012; 17 (1): 7-29.
  23. Wu C.Q, Grandi S.M, Filion K.B et al. Drospirenone - containing oral contraceptive pills and the risk of venous and arterial thrombosis: a systematic review. BJOG: an Int J Obstet Gynaecol 2013; 120 (7): 801-10.
  24. Ших Е.В. Взаимодействие компонентов витаминно - минеральных комплексов и рациональная витаминотерапия. Consilium Mеdicum. 2004; 6 (12).
  25. Zal F, Mostafavi-Pour Z, Amini F, Heidari A. Effect of vitamin E and C supplements on lipid peroxidation and GSH-dependent antioxidant enzyme status in the blood of women consuming oral contraceptives. Contraception 2012; 86 (1): 62-6.
  26. Кирющенков П.А., Шмаков Р.Г., Андамова Е.В., Тамбовцева М.А. Алгоритм клинико - гемостазиологического обследования в акушерско - гинекологической практике. Акуш. и гинекол. 2013; 1: 101-6.

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