Modern possibilities of ovarian endometrioid cyst treatment


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Abstract

The aim of the study was to evaluate the effectiveness of the procedure of removing endometrioid cysts using the PerClot local haemostatic system for the maintenance of healthy ovarian tissue, as well as revealing the possible systemic effect of this drug on hemostasis. Materials and methods. A controlled clinical randomized prospective study was conducted, targeting 82 women of reproductive age with endometrioid ovarian cysts. All patients underwent surgical treatment. The method of simple randomization of women was divided into two groups: 1 group (main) consisted of 32 women who were removed the capsule of the cyst, followed by treatment of the bed with the haemostatic system Perclot. The second group consisted of 50 patients who had been removed from the endometrioid cyst according to the traditional method, including a complete excision of the capsule, and as a hemostasis bipolar electrosurgery was used. The control group consisted of 40 healthy women of reproductive age. All participants in the study conducted a comprehensive clinical laboratory and instrumental examination. Results and conclusions. The data obtained suggest that the local method of using the new generation of hemostatic, PerClot, allows quickly and effectively to stop bleeding in combination with a low traumatic effect on healthy ovarian tissue, thereby allowing the preservation of its follicular reserve, which is especially effective in patients with endometriomas 5 cm.

About the authors

I A Lapina

N.I.Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation

Email: doclapina@mail.ru
канд. мед. наук, доц. каф. акушерства и гинекологии лечебного фак-та ФГБОУ ВО «РНИМУ им. Н.И.Пирогова» 117997, Russian Federation, Moscow, ul. Ostrovitianova, d. 1

Yu E Dobrokhotova

N.I.Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation

д-р мед. наук, проф., зав. каф. акушерства и гинекологии лечебного фак-та ФГБОУ ВО «РНИМУ им. Н.И.Пирогова» 117997, Russian Federation, Moscow, ul. Ostrovitianova, d. 1

M V Gavrilov

N.I.Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation; Clinical Hospital №1 MEDSI

канд. мед. наук, зав. отд-ния гинекологии клинической больницы №1 МЕДСИ, ассистент каф. акушерства и гинекологии лечебного фак-та ФГБОУ ВО «РНИМУ им. Н.И.Пирогова» 117997, Russian Federation, Moscow, ul. Ostrovitianova, d. 1; 143442, Russian Federation, Moscow, p. Otradnoe, Piatnitskoe sh., 6-i km

A S Sdvigov

N.I.Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation

аспирант каф. акушерства и гинекологии лечебного фак-та ФГБОУ ВО «РНИМУ им. Н.И.Пирогова» 117997, Russian Federation, Moscow, ul. Ostrovitianova, d. 1

N S Ermolenko

Clinical Hospital №1 MEDSI

акушер-гинеколог КБ №1 МЕДСИ 143442, Russian Federation, Moscow, p. Otradnoe, Piatnitskoe sh., 6-i km

References

  1. Dunselman G.A, Vermeulen N, Becker C et al. ESHRE guideline: management of women with endometriosis. Hum Reprod 2014; 29 (3): 400-12.
  2. Hudelist G, Fritzer N, Thomas A et al. Diagnostic delay for endometrisis in Austria and Germany: causes and possible consequences. Hum Reprod 2012; 27 (12): 3412-6.
  3. Humdan M, Omar S.Z, Dunselman G, Cheong Y. Influence of endometriosis on assisted reproductive technology outcomes: a systematic review and meta - analysis. Obstet. Gynecol 2015; 125 (1): 79-88.
  4. Леваков С.А., Хамошина М.Б. Эндометриоз: мировой прорыв в медикаментозном лечении. М.: StatusPraesents, 2012.
  5. Стрижаков А.Н., Давыдов А.И. Клинические лекции по акушерству и гинекологии. М.: ГЭОТАР-Медиа, 2010; с. 260-97.
  6. Ercan C.M, Sakinci M, Duru N.K et al. Antimullerian hormone levels after laparoscopic endometrioma stripping surgery. Gynecol Endocrinol 2010; 26 (6): 468-72. doi: 10.3109/09513591003632134
  7. Лапина И.А., Озолиня Л.А., Патрушев Л.И. и др. Особенности системы гемостаза у пациенток с эндометриоидными кистами яичников. Гинекология. 2015; 17 (3): 9-12.
  8. Сапрыкина Л.В., Доброхотова Ю.Э., Сапрыкина О.А. Эндометриоз: гормональная терапия с позиций патогенеза. Эффективная фармакотерапия. Акушерство и гинекология. 2015; 3: 10-4.

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