Prediction of ischemic stroke outcome during thrombolytic therapy

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Abstract

The problem of ischemic stroke in the Russian Federation occupies a leading place in the structure of causes of mortality. Among all treatment methods, the systemic thrombolytic therapy with a recombinant tissue plasminogen activator is regarded as the most effective one.

This review focuses on clinical studies of the safety and effectiveness of this type of treatment, as well as on prognostically unfavorable factors inducing the hemorrhagic transformation of ischemic stroke.

About the authors

Yu. D. Minina

Samara Regional Clinical Hospital named after V.D. Seredavin

Author for correspondence.
Email: jminina1988@gmail.com
ORCID iD: 0000-0002-2992-6451

neurologist

Russian Federation, Samara

V. A. Kalinin

Samara State Medical University

Email: jminina1988@gmail.com
ORCID iD: 0000-0003-3233-8324

PhD, Professor of Department of neurology and neurosurgery

Russian Federation, Samara

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Copyright (c) 2020 Minina Y.D., Kalinin V.A.

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