Rol' kletok vrozhdennogo immuniteta v obespechenii uspekha beremennosti na rannikh srokakh gestatsii

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Abstract

The innate immunity plays an important role in the development and maintenance of the immune balance at the fetal-maternal interface. NK and macrophages dominate in decidua at early stages of pregnancy. Interaction of innate immunity cells and invasive cytotrophoblast is a key factor defining regulation of maternal immune response and the development of placental tissues at early gestation period.

About the authors

Natalya Yuryevna Sotnikova

V. N. Gorodkov Research Institute of Maternity and Childhood, Ministry of Healthcare of the Russian Federation

Email: niimid.immune@mail.ru
MD, professor, head of laboratory

Yuliya Stanislavovna Antsiferova

V. N. Gorodkov Research Institute of Maternity and Childhood, Ministry of Healthcare of the Russian Federation

Email: niimid.immune@mail.ru
senior scientific worker

Natalya Vladimirovna Kroshkina

V. N. Gorodkov Research Institute of Maternity and Childhood, Ministry of Healthcare of the Russian Federation

Email: niimid.immune@mail.ru
PhD, scientific worker

Dmitriy Nikolayevich Voronin

V. N. Gorodkov Research Institute of Maternity and Childhood, Ministry of Healthcare of the Russian Federation

Email: niimid.immune@mail.ru
PhD, scientific worker

References

  1. Роль IFNγ в регуляции функциональной активности децидуальных естественных киллеров при беременности /Сотникова Н. Ю. [и др.] // Иммунология. — 2010. — № 3 (31). — С. 136–139.
  2. Сельков С. А., Павлов О. В. Плацентарные макрофаги. — М.: Товарищество научных изданий КМК, 2007. — 186 с.
  3. Сотникова Н. Ю. Иммунные механизмы регуляции инвазии трофобласта // Российский иммунологический журнал. — 2012. — Т. 6 (14), № 2(1). — С. 9–13.
  4. Berger J. P., Akiyama T. E., Meinke P. T. PPARs: therapeutic targets for metabolic disease // Trends. Pharmacol. Sci. — 2005. — Vol. 26. — P. 244–251.
  5. Bulmer J. N., Williams P. J., Lash G. E. Immune cells in the placental bed // Int. J. Dev. Biol. — 2010. — Vol. 54. — P. 281–294.
  6. Cooper M. A., Fehniger T. A., Caligiuri M. A. The biology of human natural killer — cell subsets // Trends. Immunol. — 2001. — Vol. 22. — P. 633–640.
  7. Curry T. S., Osteen K. G. The matrix metalloproteinase system: changes, regulation and impact throughout the ovarian and uterine reproductive cycle // Endocrine Rewiews. — 2003. — Vol. 24, N. 4 — P. 428–465.
  8. Evidence implicating peroxisome proliferatoractivated receptor–g in the pathogenesis of preeclampsia / McCarthy F. P. [et al.] // Hypertension. — 2011. — Vol. 58. — P. 882–887.
  9. Expression and function of PPARgamma in rat placental development / Asami-Miyagishi R. [et al.] // Biochem. Biophys. Res. Commun. — 2004. — Vol. 315. — P. 497–501.
  10. HLA-E is expressed on trophoblast and interacts with CD94/NKG2 receptors on decidual NK cells / King A. [et al.] // Eur. J. Immunol. — 2000. — Vol. 30, N. 6. — P. 1623–1631.
  11. Human placental peroxisome proliferator-activated receptor delta and gamma expression in healthy pregnancy and in preeclampsia and intrauterine growth restriction / Rodie V. A. [et al.] // J. Soc. Gynecol. Investig. — 2005. — Vol. 12. — P. 320–329.
  12. Koga K., Mor G. Toll-like receptors at the maternal-fetal interface in normal pregnancy and pregnancy disorders // Am. Journal Reprod. Immunol. — 2010. — Vol. 63, N. 6. — P. 587–600.
  13. Kusumi M., Yamashita T., Fujii T., Nagamtsu T. Expression patterns of lectin-like natural killer receptors, inhibitory CD94/NKG2A, and activating CD94/NKG2C on decidual CD56bright natural killer cells differ from those on peripheral CD56dim natural killer cells // J. Reprod. Immunol. — 2006. — Vol. 70, N. 1–2. — P. 33–42.
  14. Lanier L. L. NK cell recognition // Annu. Rev. Immunol. — 2005. — Vol. 23. — P. 225–274.
  15. Manaster I., Mandelboim O. The unique properties of uterine NK cells // Am. J. Reprod. Immunol. — 2010. — Vol. 63. — P. 434–444.
  16. McCarthy F. P., Delany A. C., Kenny L. C., Walsh S. K. PPAR-g- a possibl drug target for complicated pregnancies // British J. Pharmacology. — 2013. — Vol. 168. — P. 1074–1085.
  17. McCracken S. A., Gallery E., Morris J. M. Pregnancy-specific down regulation of NF-kappaB expression in T cells in humans is essential for the maintenance of the cytokine profile required for pregnancy success // J. Immunology. — 2004. — Vol.172. — P. 4583–4591.
  18. Moffett-King A. Natural killer cells and pregnancy // Nat. Rev. Immuol. — 2002. — Vol. 2, N 9. — P. 656–663.
  19. Mourik van M. S., Macklon N. S., Heijnen C. J. Embryonic implantation: cytokines, adhesion molecules, and immune cells in establishing an implantation environment // J. Leukoc.Biol. — 2009. — Vol. 85, N 1. — P. 4–19.
  20. Munoz-Suano A., Hamilton A. B., Betz A. G. Gimme shelter: the immune system during pregnancy // Immunological Reviews. — 2011. — Vol. 241. — P. 20–38.
  21. Nagamatsu T., Schust D. J. The immunomodulatory roles of macrophages at the maternal-fetal interface // Reprod. Sci. — 2010. — Vol. 17, N. 3. — P. 209–218.
  22. NK cell regulation of T cell-mediated responses / Zingoni A. [et al.] // Mol. Immunol. — 2005. — Vol. 42. — P. 451–454.
  23. Otun H. A., Lash G. E., Innes B. A., Bulmer J. N. Effect of tumour necrosis factor-α in сombination with interferon-γ on first trimester extravillous trophoblast invasion // J. Reprod. Immunol. — 2011. — Vol. 88. — P. 1–11.
  24. Parham P. NK Cells and Trophoblasts: partners in pregnancy // J. Exp. Med. — 2004. — Vol. 200, N. 8. — P. 951–955.
  25. Peroxisome proliferator-activated receptors: new players in the field of reproduction / Toth B. [et al.] // Am. J. Reprod. Immunol. — 2007. — Vol. 58. — P. 289–310.
  26. PPAR gamma represses VEGF expression in human endometrial cells: implications for uterine angiogenesis / Peeters L. L. [et al.] // Angiogenesis. — 2005. — Vol. 8. — P. 373–379.
  27. PPAR gamma/RXR alpha heterodimers control human trophoblast invasion / Tarrade A. [et al.] // J. Clin. Endocrinol. Metab. — 2001. — Vol. 86. — P. 5017–5024.
  28. Preimplantation human blastocyst-endometrial interactions: the role of inflammatory mediators / Sinderen Van M. [et al.] // Am. J. Reprod. Immunol. — 2012. — doi: 10.1111/aji.12038. URL: http: // www.ncbi.nlm.nih.gov/pubmed/advanced (дата обращения 11.04.2013).
  29. Regulation of human trophoblast migration and invasiveness / Chakraborty C. [et al.] // Can. J. Physiol. Pharmacol. — 2002. — Vol.80. — P.116–124.
  30. Sanguansermsr D., Pongcharoen S. Pregnancy immunology: decidual immune cells // Asian Pacific Journal of Allergy and Immunology. — 2008. — Vol. 26. — P. 171–181.
  31. Santoni A., Carlino C., Stabile H., Gismondi A. Mechanisms underlying recruitment and accumulation of decidual NK cells in uterus during pregnancy // Am. J. Reprod. Immunol. — 2008. — Vol. 59. — P. 417–424.
  32. Schaiff W. T., Barak Y., Sadovsky Y. The pleiotropic function of PPAR gamma in the placenta // Mol. Cell. Endocrinol. — 2006. — Vol. 249. — P. 10–15.
  33. Shapiro H., Lutaty A., Ariel A. Macrophages, meta-inflammation, and immuno-metabolism // Scientific World J. — 2011. — Vol.11. — P. 2509–2529.
  34. Sica A., Mantovani A. Macrophage plasticity and polarization: in vivo veritas // J. Clin. Invest. — 2012. — Vol. 122, N. 3. — P. 787–795.
  35. The distribution of CD56dimCD16+ and CD56brightCD16-cells are associated with prolactin levels during pregnancy and menstrual cycle in healthy women / Martinez-Garcia E. A. [et al.] // Am. Journal Reprod. Immunol. — 2011. — Vol. 65. — P. 433–437.
  36. Tripathi P., Naik S., Agrawal S. HLA-E and immunobiology of pregnancy // Tissue Antigens. — 2006. — Vol. 67, N. 3. — P. 207–213.
  37. Trophoblast-macrophage interactions: a regulatory network for the protection of pregnancy / Fest S. [et al.] // Am. J. Reprod. Immunol. — 2007. — Vol. 51. — P. 55–66.
  38. Two unique human decidual macrophage populations /Houser B. L. [et al.] // Immunol. — 2011. — Vol.186, N. 4. — P. 2633–2642.
  39. Warning J. C., McCracken S. A., Morris J. M. Balancing act: mechanisms by which the fetus avoids rejection by the maternal immune system // Reproduction. — 2011. — Vol. 141. — P. 715–724.
  40. Whitley G. S., Cartwright J. E. Cellular and molecular regulation of spiral artery remodelling: lessons from the cardiovascular field // Placenta. — 2010. — Vol. 31. — P. 465–474.

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Copyright (c) 2013 Sotnikova N.Y., Antsiferova Y.S., Kroshkina N.V., Voronin D.N.

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