The analysis of group в streptococcal clinical strains for the presence of the genes encoding for potential adherence factors and localized on the «pathogenicity islands»

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Abstract

The collection of group В streptococcal clinical strains has been analyzed for the presence of genes encoding for putative adherence and aggregation factors. The presence of the genes designated as sspB1 and sspB2 were tested by PCR and DNA hybridization. The genes under study located in GBS genome on “pathogenicity islands” were found to be heterogeneous and could be associated with urological or invasive diseases. No significant correlation between the GBS serotype and sspB genes pattern have been discovered.

About the authors

A. N. Suvorov

Research Institute of Experimental Medicine

Author for correspondence.
Email: info@eco-vector.com
Russian Federation, Saint Petersburg

А. М. Savicheva

Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott

Email: info@eco-vector.com
Russian Federation, Saint Petersburg

А. V. Glushanova

Research Institute of Experimental Medicine

Email: info@eco-vector.com
Russian Federation, Saint Petersburg

К. А. Oganyan

Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott

Email: info@eco-vector.com
Russian Federation, Saint Petersburg

К. В. Grabovskaya

Research Institute of Experimental Medicine

Email: info@eco-vector.com
Russian Federation, Saint Petersburg

О. V. Alaiceva

Research Institute of Experimental Medicine

Email: info@eco-vector.com
Russian Federation, Saint Petersburg

S. L. Zatsiorskaya

Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott

Email: info@eco-vector.com
Russian Federation, Saint Petersburg

D. J.

Research Institute of Experimental Medicine

Email: info@eco-vector.com
Russian Federation, Saint Petersburg

О. N. Arjanova

Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott

Email: info@eco-vector.com
Russian Federation, Saint Petersburg

References

Supplementary files

Supplementary Files
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1. JATS XML
2. Fig. 1. Scheme of primer DNA localization on the sspB1 and sspB2 gene sequences

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3. Fig. 2.

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4. Fig. 3.

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Copyright (c) 2005 Eсо-Vector



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