电邮这篇文章 Hemostasis system and immunomorphologic state of placenta under presence of antiphospholipid antibodies in plasma with consideration of their class and pregnancy outcome
- 作者: Kosheleva N.G.1, Zubzhitskaia L.В.1, Arzhanova О.N.1, Tyshkevich О.V.1, Gromyko Y.1, Shlyakhtenko Т.N.1, Pluzhnikova Т.A.1, Shapovalova Е.А.1
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隶属关系:
- Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
- 期: 卷 53, 编号 1 (2004)
- 页面: 22-26
- 栏目: Original study articles
- URL: https://medbiosci.ru/jowd/article/view/86971
- DOI: https://doi.org/10.17816/JOWD86971
- ID: 86971
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The present study was undertaken to investigate hemostasis system of 197 women with recurrent miscarriage: Analysis placentas by immunomorphology are studied of 41 women and of 52 women with autoimmune antibodies to β2-glycoprotein-I (β2-GPI) in placenta. There was exposed hyperactivation platelets blood of all women with antiphospholipid antibodies irrespective of groups with significantly was increased at the beginning of pregnancy and progressed with growing gestation. As result of investigation it is determined certain connection between outcome of pregnancy and activation degree platelets blood in vasculars. Was found absence influence anticardiolipin antibodies (aCL) on plasmocoagulative link hemostasis. The circulation of lupus anticoagulant (LA) was accompanied indication of hypercoagulation. In all research groups was determined significant oppression of fibrinolisis. Analysis placentas by immunomorphology was determined significantly tissue damages with LA and β2-GPI-dependent aCL.
作者简介
N. Kosheleva
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
编辑信件的主要联系方式.
Email: info@eco-vector.com
俄罗斯联邦, Saint Petersburg
L. Zubzhitskaia
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: info@eco-vector.com
俄罗斯联邦, Saint Petersburg
О. Arzhanova
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: info@eco-vector.com
俄罗斯联邦, Saint Petersburg
О. Tyshkevich
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: info@eco-vector.com
俄罗斯联邦, Saint Petersburg
Y. Gromyko
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: info@eco-vector.com
俄罗斯联邦, Saint Petersburg
Т. Shlyakhtenko
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: info@eco-vector.com
俄罗斯联邦, Saint Petersburg
Т. Pluzhnikova
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: info@eco-vector.com
俄罗斯联邦, Saint Petersburg
Е. Shapovalova
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: info@eco-vector.com
俄罗斯联邦, Saint Petersburg
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