A comparative estimation of the results of 'natural’ and 'synthetic' estrogens application in gonadal disgenesis

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Gonadal disgenesis concerns to the genetically caused forms of a delay of sexual development (DSD) in men. Despite of its rare appearance in a population, the large importance all over the world is given to a gonadal disgenesis problem. The results of the carried out research are the convincing the proof of an acceptability and expediency of hormonal replacement therapy assignment in patients with gonadal disgenesis with preparations containing estradiol valeratis in a combination with medroxyprogesteron without a dependence from the form of the diseases.

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E. Uvarova

Scientific Center for Obstetrics, Gynecology and Perinatology, Russian Academy of Medical Sciences

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Email: info@eco-vector.com
俄罗斯联邦, Moscow

E. Bogdanova

Scientific Center for Obstetrics, Gynecology and Perinatology, Russian Academy of Medical Sciences

Email: info@eco-vector.com
俄罗斯联邦, Moscow

N. Martysh

Scientific Center for Obstetrics, Gynecology and Perinatology, Russian Academy of Medical Sciences

Email: info@eco-vector.com
俄罗斯联邦, Moscow

V. Shavaeva

Scientific Center for Obstetrics, Gynecology and Perinatology, Russian Academy of Medical Sciences

Email: info@eco-vector.com
俄罗斯联邦, Moscow

T. Rudneva

Scientific Center for Obstetrics, Gynecology and Perinatology, Russian Academy of Medical Sciences

Email: info@eco-vector.com
俄罗斯联邦, Moscow

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2. Fig. 1. Echogram of the mammary glands of patient Z., 17 years old, before (a) and 3 months later (b) after taking Divitren.

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3. Fig. 2. Dynamics of changes in hormonal status while taking ZGT in patients with dysgenesis of gonads.

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4. Fig. 3. Dynamics of uterine length and endometrial thickness (cm) as a result of changes in ZGT in patients with dysgenic gonads.

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5. Fig. 4. Changes in mammary gland echostructure against the background of ZGT in patients with gonadal dysgenesis.

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