Recommendations for the prevention and correction of thrombotic complications in COVID-19

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Abstract

The new coronavirus infection caused by the SARS-CoV-2 virus (COVID-19) is characterized by a high frequency of thrombotic complications varying from venous or, more rarely, arterial thrombosis to the development of disseminated intravascular coagulation (DIC) and/or diffuse pulmonary vascular microthrombosis, which aggravates the disease and becomes one of the leading causes of deaths. Timely and personalized anticoagulant thromboprophylaxis with low-molecular-weight heparins may prevent a severe course of the disease and improve outcomes. This applies to outpatients, hospitalized patients and patients in the early post hospital period. In the future, to develop comprehensive and evidence-based guidelines on the management of patients with COVID-19, it is necessary to conduct comprehensive systematic studies and comparative clinical trials of prophylaxis and treatment of hemostatic disorders in patients with COVID-19.

About the authors

S I Safiullina

Kazan (Volga Region) Federal University; “Aibolit” medical center

Author for correspondence.
Email: svetlana.ild.safiullina@gmail.com
Russian Federation, Kazan, Russia; Kazan, Russia

R I Litvinov

Kazan (Volga Region) Federal University

Email: svetlana.ild.safiullina@gmail.com
Russian Federation, Kazan, Russia

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© 2020 Safiullina S.I., Litvinov R.I.

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